Gene description for MLANA |
Gene name |
melan-A |
Gene symbol |
MLANA |
Other names/aliases |
MART-1 MART1 |
Species |
Homo sapiens |
Experiment description of studies that identified MLANA in Melanoma cells |
1
|
Experiment ID | 12 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Western blotting
|
PubMed ID |
15478216
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of melanoma-derived exosomes by two-dimensional polyacrylamide gel electrophoresis and mass spectrometry. |
Authors | Mears R, Craven RA, Hanrahan S, Totty N, Upton C, Young SL, Patel P, Selby PJ, Banks RE |
Journal name |
PROTEOMICS
|
Publication year | 2004 |
Sample | Melanoma cells |
Sample name | MeWo SK-MEL-28 |
Isolation/purification methods | Filtration Ultracentrifugation Sucrose density gradient |
Flotation density | 1.13-1.20 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [4700 Proteomics Analyzer] Western blotting |
EV-TRACK |
-
|
|
|
2
|
Experiment ID | 24 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Western blotting
|
PubMed ID |
11231627
|
Organism | Homo sapiens |
Experiment description | Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming. |
Authors | Wolfers J, Lozier A, Raposo G, Regnault A, Thé C, Masurier C, Flament C, Pouzieux S, Faure F, Tursz T, Angevin E, Amigorena S, Zitvogel L. |
Journal name |
NM
|
Publication year | 2001 |
Sample | Melanoma cells |
Sample name | Fon Mel-888 |
Isolation/purification methods | Differential centrifugation Sucrose density gradient |
Flotation density | 1.14 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
3
|
Experiment ID | 619 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Melanoma cells |
Sample name | MALME-3M |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
4
|
Experiment ID | 621 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Melanoma cells |
Sample name | SK-MEL-2 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
5
|
Experiment ID | 622 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Melanoma cells |
Sample name | SK-MEL-28 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
6
|
Experiment ID | 624 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Melanoma cells |
Sample name | UACC-257 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
7
|
Experiment ID | 986 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Microvesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
25261472
|
Organism | Homo sapiens |
Experiment description | Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment. |
Authors | Liang Y, Eng WS, Colquhoun DR, Dinglasan RR, Graham DR, Mahal LK. |
Journal name |
J Biol Chem.
|
Publication year | 2014 |
Sample | Melanoma cells |
Sample name | SK-MEL-5 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140188: EV-METRIC:22%
|
|
|